How Common Is It To Be A CF Carrier?

Can you get CF if only one parent is a carrier?

If only one parent is a carrier of a defective CF gene, the child will not have CF.

But there is a 50% (1-in-2) chance that the child will be a CF carrier.

If both parents are carriers, there is a 25% (1-in-4) chance that the child will have CF, and a 50% chance that the child will be a carrier..

Does everyone have the cystic fibrosis gene?

Every person has two copies of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. A person must inherit two copies of the CFTR gene that contain mutations — one copy from each parent — to have cystic fibrosis. Some genetic diseases, such as cystic fibrosis, are caused by mutations in a single gene.

Is Cystic Fibrosis more common in one ethnicity?

Cystic fibrosis is a common genetic disease within the white population in the United States. The disease occurs in 1 in 2,500 to 3,500 white newborns. Cystic fibrosis is less common in other ethnic groups, affecting about 1 in 17,000 African Americans and 1 in 31,000 Asian Americans.

How can a child inherit cystic fibrosis if neither parent has the disease?

A child can inherit CF only if both parents carry a CF gene (that is, each parent either has CF or is a carrier) and both parents pass the CF gene on to their child. There is nothing that parents do to cause CF in their child and usually they do not know that they are carriers of a CF gene.

How old is the oldest living person with cystic fibrosis?

Senior citizens with cystic fibrosis Thanks to advances in DNA testing, doctors are identifying more and more people with CF for the first time well into their 50s, 60s, and 70s. The oldest person diagnosed with CF for the first time in the U.S. was 82, in Ireland was 76, and in the United Kingdom was 79.

What are the odds of being a cystic fibrosis carrier?

About one in every 35 Americans is a symptomless carrier of the defective CFTR gene. Only about one of every 3,000 Caucasian newborns has CF. We know there are more than 1,700 mutations of the CFTR gene.